pySMT makes working with Satisfiability Modulo Theory simple.

Among others, you can:

* Define formulae in a solver independent way in a simple and
  inutitive way,
* Write ad-hoc simplifiers and operators,
* Dump your problems in the SMT-Lib format,
* Solve them using one of the native solvers, or by wrapping any
  SMT-Lib complaint solver.